Cerebral aneurysms are a life-threatening condition and currently, too simplified models are used to decide on treatment or regular follow-up. The risk of aneurysm growth or rupture is difficult to assess and hemodynamic factors are considered as new imaging biomarkers. 4D-flow MRI is employed for the comprehensive in-vivo analysis of hemodynamics.
We previously investigated the relationship of size and morphology with hemodynamics of different intracranial aneurysms (IA). 4D flow MRI demonstrated the influence of lesion size and morphology on aneurysm hemodynamics suggesting the potential of 4D-flow MRI to assist in the classification of individual aneurysms. Future longitudinal studies and correlation with aneurysm risk factors or aneurysm growth/rupture are required to evaluate the utility of hemodynamic markers for improved risk assessment and therapy planning

Primary contact: Susanne Schnell (PhD)
Investigators: Susanne Schnell (PhD), TBD
Collaborations: Northwestern University (Ann Ragin, Maria Aristova, Sameer Ansari, Mike Hurley)